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Duloxetine (Cymbalta)
Drug Interactions

Dr. Ron Daulton, Jr.

I’ve created a chart below that shows the medications that Duloxetine (Cymbalta) can potentially interact with.

If you are taking any of these medications together, you should discuss it with your doctor immediately. Please do not stop taking any medications without speaking to your doctor about it first.

In addition to that, this is not a complete list of the possible drug interactions that can occur (these are the most common ones). However, I’ve tried to be as thorough and complete as possible. So it’s important that you speak with your doctor or pharmacist about any potential interactions that could take place with the medications you are taking.

Do not take any of this medication with alcohol.


Duloxetine (Cymbalta)

Abilify (aripiprazole)
Aspir–Low (aspirin)
Aspirin Low Strength (aspirin)
Ativan (lorazepam)
Coumadin (warfarin)
Crestor (rosuvastatin)
Fentanyl Transdermal System (fentanyl)
Fish Oil (omega-3 polyunsaturated fatty acids)
Lantus (insulin glargine)
Lyrica (pregabalin)
MiraLax (polyethylene glycol 3350)
OxyContin (oxycodone)
Paracetamol (acetaminophen)
Seroquel (quetiapine)
Tylenol (acetaminophen)
Vicodin (acetaminophen / hydrocodone)
Vitamin B12 (cyanocobalamin)
Vitamin C (ascorbic acid)
Vitamin D2 (ergocalciferol)
Vitamin D3 (cholecalciferol)

Here is a list of other medications you can learn about:

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