Anticonvulsants For Spinal Disc Pain:
Side Effects

What you will learn in this article:

- Anticonvulsants, traditionally used for seizures, have shown promise in managing spinal disc pain by modulating nerve activity and providing targeted relief.

- While they offer a potential alternative to traditional painkillers, they come with side effects like dizziness, gastrointestinal issues, and weight changes.

- Long-term effects on spinal health, potential interactions with other medications, and dosage considerations are vital aspects to consider when using anticonvulsants for spinal pain.

- Expert opinions lean towards the benefits of anticonvulsants, but it's essential to weigh these against potential risks and side effects for a holistic approach to pain management.

Anticonvulsants, renowned for their role in managing seizures, have recently been spotlighted for their potential in addressing spinal disc pain.

Their unique mechanism, which focuses on stabilizing nerve activity, positions them as a compelling contender against traditional painkillers.

But every silver lining has its cloud.

This article dives deep into the side effects associated with anticonvulsants in the context of spinal disc pain.

From the common reactions many experience to the intricate considerations when using them specifically for spinal issues, we'll lay it all out.

By journey's end, you'll have a holistic view, enabling you to make informed decisions about this treatment path.

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Anticonvulsants: A Brief Overview

Anticonvulsants have long been the stalwarts in the medical world, primarily championed for their role in managing seizures.

These medications, with their intricate mechanisms, work by stabilizing the erratic electrical activity in the brain, preventing the sudden surges that lead to convulsive episodes.

Over the years, they've been a lifeline for countless individuals with epilepsy, ensuring a semblance of normalcy in their lives.

However, the narrative began to evolve when patients on anticonvulsants for seizures reported an unexpected benefit: a reduction in chronic pain.

This revelation piqued the interest of the medical community, leading to investigations into their potential for pain management.

The results were promising, especially for those with nerve-related pain, including the agonizing discomfort stemming from spinal disc issues.

This serendipitous discovery marked the beginning of a shift, positioning anticonvulsants not just as seizure suppressants but also as potential warriors in the battle against spinal disc pain.

The Mechanism Behind the Relief

Anticonvulsants for Spinal Disc Pain | Side Effects

Diving into the heart of anticonvulsants, it's essential to understand their nuanced interaction with our nervous system.

These medications primarily function by modulating the activity of neurotransmitters, the brain's chemical messengers.

By tweaking the balance of these neurotransmitters, anticonvulsants ensure that messages between nerve cells are transmitted smoothly and without erratic surges.

Additionally, they influence ion channels, gateways that control the flow of charged particles in and out of nerve cells.

By regulating these channels, anticonvulsants create a stable electrical environment, preventing the wild electrical storms that lead to seizures and, as discovered, pain.

Now, when juxtaposed with traditional painkillers, anticonvulsants present a compelling case.

While most painkillers work by blocking pain signals or altering pain perception, anticonvulsants target the very root of the problem.

They address the nerve activity that often underlies chronic pain, especially the type associated with spinal disc issues.

This targeted approach, combined with fewer side effects compared to opioids and NSAIDs, positions anticonvulsants as a potential powerhouse in the realm of pain management.

For many, they might just be the alternative they've been searching for, offering relief without the baggage of traditional painkillers.

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Common Side Effects

While anticonvulsants have showcased their potential in the realm of spinal pain management, they're not without their quirks.

One of the most frequently reported side effects is dizziness.

Many individuals, especially when starting their anticonvulsant journey, report a sense of unsteadiness or lightheadedness.

This can be accompanied by fatigue, making them feel drained or lacking the usual zest for life.

But that's not all. The gut isn't left untouched either.

Gastrointestinal issues, ranging from mild nausea to an upset stomach, have been noted.

Some even experience bouts of diarrhea or constipation, making dietary adjustments a potential necessity when on these medications.

And then there's the matter of weight. A number of anticonvulsant users have reported weight gain, which can be a concern for many.

This change in weight might be accompanied by other physical shifts, such as swelling in certain parts of the body or changes in appetite.

It's essential to keep an eye on these transformations, ensuring they don't escalate into more significant health concerns.

While the relief they offer is undeniable, being aware of these side effects ensures you're not caught off guard and can make informed decisions about your health journey.

The following is a more thorough list of the possible side effects that can occur with these medications.

Everyone is different and you may experience a side effect that is not on the list.

If you are experiencing a new symptom while taking any of these medications, you should bring that to your doctor’s attention immediately.

Allergic reaction: hives; fever; swollen glands; painful sores in or around your eyes or mouth; difficulty breathing; swelling of your face, lips, tongue, or throat

Mood or behavior changes, anxiety, depression, feeling agitated, hostile, restless, hyperactive (mentally or physically), thoughts about suicide or hurting yourself


Fever, swollen glands, body aches, flu symptoms

Skin rash, easy bruising or bleeding, severe tingling, numbness, pain, muscle weakness

Upper stomach pain, loss of appetite, dark urine, jaundice (yellowing of the skin or eyes)

Chest pain, irregular heart rhythm, feeling short of breath

Confusion, nausea and vomiting, swelling, rapid weight gain, urinating less than usual or not at all

New or worsening cough, fever, trouble breathing

Rapid back and forth movement of your eyes

Changes in behavior

Memory problems

Trouble concentrating

Acting restless, hostile, or aggressive

Dizziness, drowsiness, weakness, tired feeling

Nausea, diarrhea, constipation

Blurred vision


Breast swelling

Dry mouth

Loss of balance or coordination

Allergic reaction: hives; fever; swollen glands; painful sores in or around your eyes or mouth; difficulty breathing; swelling of your face, lips, tongue, or throat

Mood or behavior changes, anxiety, depression, feeling agitated, hostile, restless, hyperactive (mentally or physically), thoughts about suicide or hurting yourself

Skin rash, easy bruising or bleeding, severe tingling, numbness, pain, muscle weakness

Memory problems

Trouble concentrating

Dizziness, drowsiness, weakness, tired feeling

Breast swelling

Dry mouth

Loss of balance or coordination

Muscle pain, weakness, or tenderness (especially if you also have a fever and feel tired)

Vision problems

Swelling in your hands or feet, rapid weight gain



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Specific Considerations for Spinal Pain Management

Navigating the world of spinal pain management with anticonvulsants requires a keen awareness of potential interactions.

If you're already on medications for spinal pain, introducing anticonvulsants into the mix can be a delicate dance.

Some drugs might amplify the effects of anticonvulsants, while others could diminish their efficacy.

It's crucial to have an open dialogue with your healthcare provider, ensuring that the combination doesn't lead to unforeseen complications.

Beyond interactions, there's the question of long-term effects on spinal health.

While anticonvulsants have been extensively studied for their role in managing seizures, their prolonged use specifically for spinal pain is still a relatively uncharted territory.

There's a need to monitor any changes in spinal health, ensuring that the medication doesn't inadvertently exacerbate any underlying issues or introduce new ones.

Lastly, dosage is a critical factor. The amount of anticonvulsant required to manage seizures can differ significantly from what's needed for spinal pain.

Often, lower doses are effective for pain management, but this isn't a one-size-fits-all scenario.

It's essential to start with a conservative dose, gradually adjusting based on your body's response and the relief experienced.

Regular check-ins with a medical professional are paramount, ensuring that the dosage remains optimal for your unique needs and doesn't veer into the territory of overmedication.

Weighing the Pros and Cons

Anticonvulsants, with their nerve-stabilizing prowess, have undeniably carved a niche in the realm of spinal pain management.

Their targeted approach, focusing on the root cause of the pain rather than merely masking it, offers a glimmer of hope for many.

This means potentially fewer doctor visits, reduced dependency on multiple medications, and a chance at a life with diminished pain.

For many, the relief experienced can be life-altering, bringing back the joy of simple activities once taken for granted.

However, this silver lining isn't devoid of clouds.

The side effects, ranging from dizziness to gastrointestinal issues, can be a deterrent for some.

There's also the matter of potential interactions with other medications and the unknowns associated with long-term use specifically for spinal pain.

It's a balance of potential relief against the backdrop of these considerations.

Expert opinions, while largely positive, come with their own set of cautions. The consensus? It's about individual fit, weighing the benefits against the potential risks, and making an informed decision in tandem with a trusted healthcare provider.


You're not alone in that thought! Anticonvulsants were primarily designed for seizures, but their ability to stabilize nerve activity has made them a potential knight in shining armor for spinal pain sufferers. It's like discovering your favorite superhero has another hidden power.

While anticonvulsants can offer significant relief, they come with side effects like dizziness, weight gain, and some tummy troubles. But here's the thing: every medication has its quirks. It's all about weighing the relief against the potential hiccups.

Torn between the old and the new? Anticonvulsants, with their targeted approach, dive deeper into the root cause of pain, unlike traditional painkillers that often just mask the symptoms. It's like choosing between a band-aid and a cure. But remember, everyone's body is unique, so it's about finding what resonates with you.

The long-term effects of anticonvulsants, specifically for spinal pain, are still being studied. It's essential to monitor any changes and stay in close contact with your healthcare provider. After all, knowledge is power.

Many experts are leaning towards anticonvulsants as a promising avenue for spinal pain management. But, as with everything, it's crucial to find a trusted expert and ensure their recommendations align with your unique needs. Trust, but verify.

The dosage for spinal pain often differs from that for seizures. It's typically tailored based on individual needs and the severity of the pain. Always consult with a professional before making any changes. It's better to be safe than sorry.


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Shinu, P., Morsy, M., Nair, A. B., Al Mouslem, A. K., Venugopala, K., Goyal, M., Bansal, M., Jacob, S., & Deb, P. (2022). Novel Therapies for the Treatment of Neuropathic Pain: Potential and Pitfalls.

Fukasawa, H., Muratake, H., Nagae, M., Sugiyama, K., & Shudo, K. (2014). Transdermal administration of aqueous pregabalin solution as a potential treatment option for patients with neuropathic pain to avoid central nervous system-mediated side effects.

Dr. Ron Daulton, Jr.

About the Author

Dr. Ron Daulton, Jr., an acclaimed chiropractor, esteemed educator, and inspiring author, has devoted his life to fostering understanding of natural healthcare and enhancing well-being across society.

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